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Is ADHD Genetic or Hereditary?

Dorianne Green
Written by:
Dorianne Green
MD
Dr. Henry Bradford
Medical Reviewer:
Dr. Henry Bradford
MD

Highlights

  • Genetics plays a significant role in the development of attention deficit hyperactivity disorder (ADHD), but environmental factors also have an influence.
  • The inheritance pattern of ADHD is complex and involves multiple genes.
  • Having a biological parent or sibling with ADHD increases the chances of a child having ADHD.
  • There are currently no genetic tests available for ADHD, and it is still diagnosed on symptoms by a healthcare professional.

You might be reading this post because you have a parent with ADHD, think you might have similar symptoms, and wonder if ADHD is hereditary. Or, perhaps your child has just been diagnosed with ADHD, and you recognize their behavior in yourself. If this sounds like you, you can also consider taking this free online ADHD screening test.

Another possibility is that you already have an ADHD diagnosis, are thinking of starting a family, and want to know the implications.

Whatever the reason, we’ll answer all your questions about the genetic aspect of ADHD and whether it runs in families.

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What Is the Cause of ADHD? Is It Hereditary?

Attention deficit hyperactivity disorder (ADHD) is a complex disorder that doesn’t have an exact cause. Instead, it is a mixed result of a person’s genes and specific circumstances (environmental factors) that they might have experienced.

The Role of Genetics in ADHD

Evidence suggests ADHD is largely a genetic disease with a well-established heritability of up to 80% [1*] . This doesn’t mean that 80% of children whose parents have ADHD will inherit it, but that genetics play most of the role in ADHD risk. 

Basically, genetics predispose someone to ADHD, but the person’s environment also has an influence.

Think of ADHD like a chocolate cake: 

  • Imagine the hereditary aspect and genes being the strict recipe steps that have about an 80% effect on the product outcome. 
  • But, 20% is influenced by external circumstances: how the batter is mixed, the quality of the ingredients, and whether the oven is working properly. 

Every cake made from the same recipe might look or taste slightly different, but they are still chocolate cakes because the basic recipe has the biggest influence on the result. 

In the same way, every person with ADHD is different, mostly influenced by genetics but also by circumstances and environmental factors.

How has this been worked out?

Family Studies

Family studies have shown that:

"When assessing a patient for ADHD for the first time, we always review their family history. It's common to identify one or more first-degree relatives who demonstrate significant signs of ADHD, even if undiagnosed. It often becomes an ‘Aha’ moment for patients!"
Dr. Henry Bradford, MD
Medical provider at MEDvidi

Identical Twin Studies

Because identical twins have exactly the same genes, any behavioral differences between them can be assumed to have unique environmental causes [3*] . Generally speaking, a child has a 70 to 80% chance [4*] of having ADHD if their identical twin does.

Adoption Studies

An adopted child shares no DNA with their parents, so this eliminates the genetic side of things. This allows the effect of the shared environment to be assessed on ADHD in adopted and biological children. Adoption studies suggest that genetics outweigh the environment in the risk of developing ADHD.

Interestingly, family and twin studies also show a specific genetic overlap between ADHD and other mental health disorders, such as conduct disorder, oppositional defiant disorder, substance abuse problems, and autism spectrum disorder.

The way ADHD is passed through generations is complex and the result of more than one genetic mutation. It might surprise you that research has found [5*] :

  • 7300 small differences in DNA associated with a slight increase in the risk of ADHD. The more there are in a person, the higher the risk.
  • 76 risk genes for ADHD; these specific genes carry a much higher risk for ADHD if inherited.

Most of these DNA differences influence areas in the brain that are important for attention, memory, movement, and reward. In fact, ADHD is classified as a neurodevelopmental, or in simple terms, brain development disorder.

See a licensed medical provider to get treatment for ADHD and learn how to avoid negative effects of ADHD on your life.

The ADHD Brain

ADHD brains function differently from non-ADHD brains. This is because of how ADHD brains are built and how their nerve cells communicate, changing the way a person with ADHD thinks and behaves.

  • Brain Chemistry. Chemical differences in the ADHD brain are related mainly to the neurotransmitter dopamine. Dopamine is a brain chemical that helps someone feel rewarded; it’s a feel-good nerve cell messenger that helps people stay motivated and on track. 

Certain areas of ADHD brains have fewer dopamine receptors [6*] and dopamine transporters [7*] ; this means that dopamine isn’t moved into the nerves where it is needed and can’t work properly.

  • Brain Structure. Many brain regions (including the frontal lobes and basal ganglia, although this is not important to know) in ADHD brains are smaller [8*] than in non-ADHD brains, affecting brain function.
    Basal ganglia are important for controlling movement, behavior, and decision-making.
    The frontal lobe is important for intelligence and creativity. It is home to working memory [9*] , which has temporary storage (short-term memory) and an area that can interpret information (executive function). People with ADHD are known to have poor executive working memory [10*] , which makes it difficult to focus, prioritize, and make logical decisions.

We’ve mentioned that a person’s circumstances [3*] can play a role in developing ADHD because of the effects on healthy brain formation, so what are these environmental influences?

Other Possible Causes and Risk Factors of ADHD

Some of the other factors that might affect brain development are:

1. Before birth in the womb, if a mother:

  • Experiences regular stress and trauma
  • Is exposed to pesticides
  • Smokes
  • Is not eating the correct food to stay healthy
  • Has severe infections

2. During or after birth [3*] :

  • Premature birth
  • Low birth weight
  • Childhood stroke
  • Brain injury
  • Lead expose
  • Immune response to bacterial infection (streptococcal) affects the basal ganglia
  • Childhood abuse or neglect

Some of these, like brain injury, have lasting effects [3*] on ADHD developmental trajectories or paths, while others, like an immune response, might impact only a point in time. If you are experiencing ADHD symptoms, online ADHD treatment at MEDvidi provides access to medical professionals who can offer a comprehensive evaluation and a personalized treatment plan.

"ADHD is influenced by both genetic and environmental factors. By the time a child reaches grade school, their genetic risk and early environmental influences are largely established. If the genetic predisposition is strong, the likelihood of experiencing ADHD symptoms is high. However, ongoing environmental factors can either worsen or mitigate the severity of those symptoms."
Dr. Henry Bradford, MD
Medical provider at MEDvidi

Common Misconceptions About the ADHD Causes

We’ve chatted about some of the likely environmental triggers, causes, and risk factors of ADHD that affect brain biology. Now let’s discuss other things that are often thought to be causes but are not.

Lack of Nutrients and Microelements

We’ll first look at nutritional factors as a cause of ADHD because they are controversial. There have been theories that deficiencies [11*] of magnesium, zinc, iron, vitamin D, and omega-3 fatty acids are risk factors, but this isn’t definitely proven.

Obviously, a healthy diet is essential for a healthy brain. Importantly, though, a healthy diet in childhood can have a significant effect on lowering the risk of ADHD diagnosis compared to those who are not. This is particularly true for a Mediterranean diet [11*] of vegetables, fruit, beans, nuts, whole grains, and fish.

Parenting Practices

A parent’s influence ends with the genetic factors of ADHD. Although poor parenting practices, such as excessive punishment, high control and unrealistic rules, poor boundaries, and low emotional support, may make the ADHD symptoms worse, they do not cause the disorder.

Video Games and TV Watching

Excess time spent on screens is not a cause of attention deficit hyperactivity disorder but, rather, might worsen ADHD symptoms; games and TV act as distractions that make focusing more difficult.

A High Sugar Diet

There has always been a theory that eating too much sugar causes ADHD, but this is not proven. In fact, some studies think that craving for and eating sugar might be a result of the disorder and not a cause of it.

What to Do When You Have a Family History of ADHD

Now that you know genes play a role, and if you have a family history of ADHD, monitor yourself for the symptoms, as you could inherit this common disorder [4*] .

Even though there is a strong genetic link, genetic testing is not used [1*] to diagnose ADHD as there are too many genetic variants associated with it. Instead, the diagnosis is made by a mental health professional on symptoms of low attention, high activity, and impulsivity.

Importantly, getting a diagnosis sooner rather than later is critical, as untreated ADHD in adults can have negative effects. So, if you suspect you may have attention deficit hyperactivity disorder, book an appointment today.

FAQs about ADHD and Heredity

The genetic component of attention deficit hyperactivity disorder can be inherited from the mother, the father [12*] , or both parents. If one parent has ADHD, the chance of their child developing ADHD is up to 56%; this is even higher if both parents have ADHD.

Yes, even though ADHD runs in families, this is not a reason for people with ADHD to avoid having children. It is not a life-threatening disease but a disorder that can be well-managed. Also, the environmental risk factors that can contribute to ADHD during pregnancy and early childhood can usually be controlled.

Males and females are equally likely to inherit ADHD [13*] ; however, males are more frequently diagnosed. This is because females present symptoms of ADHD differently than males and might go undiagnosed into adulthood.

Remember that although genetics play the biggest role in having ADHD, so does the environment the person is exposed to.

According to a 2022 CDC parents’ survey on race and ethnicity [14*] , US Black children (12%) and White children (12%) were the most often diagnosed, followed by American Indian/Alaska Native children (10%), Native Hawaiian/Pacific Islander children (6%), and Asian children (4%). Also, there are more ADHD cases in non-Hispanic children (12%) than in Hispanic children (10%).

It is likely that ADHD could skip a generation because the way it is inherited is complicated. Many genes are involved, and there are also environmental factors that influence whether ADHD is manifested.

Sources

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14 sources
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  2. A. Vélez-van-Meerbeke, C. Talero-Gutiérrez, I. Zamora-Miramón, G.M. Guzmán-Ramírez. Attention deficit hyperactivity disorder: From parents to children. Neurología. 2017;32(3):158-165.
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  3. Livingstone LT, Coventry WL, Corley RP, Willcutt EG, Samuelsson S, Olson RK, Byrne B. Does the Environment Have an Enduring Effect on ADHD? A Longitudinal Study of Monozygotic Twin Differences in Children. J Abnorm Child Psychol. 2016 Nov;44(8):1487-1501. doi: 10.1007/s10802-016-0145-9. PMID: 26993487; PMCID: PMC5027180.
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  4. Other ADHD Related Data. CHADD.
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  5. Probable Risk Genes Linked to ADHD in Large Study. ADDitude.
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  6. Magnus W, Anilkumar AC, Shaban K. Attention Deficit Hyperactivity Disorder. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
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  7. Volkow ND, Wang GJ, Kollins SH, Wigal TL, Newcorn JH, Telang F, Fowler JS, Zhu W, Logan J, Ma Y, Pradhan K, Wong C, Swanson JM. Evaluating dopamine reward pathway in ADHD: clinical implications. JAMA. 2009 Sep 9;302(10):1084-91. doi: 10.1001/jama.2009.1308. Erratum in: JAMA. 2009 Oct 7;302(13):1420. PMID: 19738093; PMCID: PMC2958516.
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  8. Curatolo P, D'Agati E, Moavero R. The neurobiological basis of ADHD. Ital J Pediatr. 2010 Dec 22;36(1):79. doi: 10.1186/1824-7288-36-79. PMID: 21176172; PMCID: PMC3016271.
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  9. Funahashi S. Working Memory in the Prefrontal Cortex. Brain Sci. 2017 Apr 27;7(5):49. doi: 10.3390/brainsci7050049. PMID: 28448453; PMCID: PMC5447931.
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  10. Kofler, M. J., Singh, L. J., Soto, E. F., Chan, E. S. M., Miller, C. E., Harmon, S. L., & Spiegel, J. A. (2020). Working memory and short-term memory deficits in ADHD: A bifactor modeling approach. Neuropsychology, 34(6), 686–698.
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  11. Lange KW, Lange KM, Nakamura Y, Reissmann A. Nutrition in the Management of ADHD: A Review of Recent Research. Curr Nutr Rep. 2023 Sep;12(3):383-394. doi: 10.1007/s13668-023-00487-8. Epub 2023 Jul 28. PMID: 37505402; PMCID: PMC10444659.
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  12. Thissen AJ, Rommelse NN, Altink ME, Oosterlaan J, Buitelaar JK. Parent-of-origin effects in ADHD: distinct influences of paternal and maternal ADHD on neuropsychological functioning in offspring. J Atten Disord. 2014 Aug;18(6):521-31. doi: 10.1177/1087054712443159. Epub 2012 May 24. PMID: 22628139.
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  13. Martin J, Taylor MJ, Rydell M, Riglin L, Eyre O, Lu Y, Lundström S, Larsson H, Thapar A, Lichtenstein P. Sex-specific manifestation of genetic risk for attention deficit hyperactivity disorder in the general population. J Child Psychol Psychiatry. 2018 Aug;59(8):908-916. doi: 10.1111/jcpp.12874. Epub 2018 Feb 16. PMID: 29451303; PMCID: PMC6055636.
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Dorianne Green
Written by:
Dorianne Green
MD
Dr. Henry Bradford
Medical Reviewer:
Dr. Henry Bradford
MD
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This article contains scientific references. The numbers
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