Content

Exploring the Link Between Hypermobility and ADHD

Dorianne Green
Author
Dorianne Green
Medical Writer
Dr. Michael Chichak
Medical Reviewer
Dr. Michael Chichak
MD

Highlights

  • Recent studies have found that hypermobility is related to ADHD, although the exact reason is unknown. 
  • The combination of ADHD plus joint pain is often an indicator of hypermobility. However, being hypermobile does not necessarily mean you have ADHD, and vice versa.
  • Managing hypermobility is necessary only when it produces symptoms; when it does, the primary focus is to reduce pain, most commonly through physical therapy.
  • Coexisting ADHD and painful hypermobility are often associated with other physical symptoms: clumsiness from poor proprioception, dizziness, fainting, and fatigue from autonomic nervous system issues.

Symptomatic hypermobility and ADHD are traditionally seen as separate conditions[1] , each with unique challenges, assessed and managed by different medical specialties. But recent research suggests differently.

This article will give you a better understanding of the link between ADHD and hypermobility, what to look out for, and how to manage the combination successfully.

Think you may have ADHD? Book an appointment with a licensed clinician and get your symptoms assessed online.

Is Hypermobility Linked to ADHD?

Research suggests a link between attention-deficit hyperactivity disorder (ADHD) and joint hypermobility. First, what is actually generalized joint hypermobility? A person with hypermobility can extend their joints beyond the normal limits; they are those incredibly bendy or flexible people.

Interestingly, studies find that the connection between joint hypermobility[2] and ADHD[3] can work in both directions.

ADHD diagnosis → generalized joint hypermobility

  • Adults with ADHD are almost 5 times more likely[4] to have generalized joint hypermobility than those without ADHD.
  • Around half[5] of individuals diagnosed with ADHD have generalized joint hypermobility.

Joint hypermobility syndromes → ADHD diagnosis 

  • In 15- to 18-year-olds with hEDS[6] (hypermobile Ehlers-Danlos syndrome), about 4 out of 10 had coexisting ADHD. Kids with an HSD diagnosis (hypermobility spectrum disorder) also have a strong association with ADHD, but it is less common than in those with hEDS.
  • Individuals with EDS[7] are around 6 times more likely to have an ADHD diagnosis than those without EDS.

You most likely have some idea of what ADHD is, but what are HSD and EDS?

Hypermobility, HSD, and EDS: What's the Difference?

Hypermobility is a symptom of HSD and hEDS, but you can be hypermobile and not have HSD and hEDS.

Hypermobility spectrum disorder (HSD) and Ehlers-Danlos syndrome (EDS) are rare genetic connective tissue disorders, sometimes also called[8] symptomatic joint hypermobility syndromes. There are 13 types of EDS, including hypermobile Ehlers-Danlos syndrome (hEDS).

HSD and hEDS[6] symptoms are similar, making daily life difficult:

  • Generalized hypermobility
  • Joint pain
  • Poor proprioception (the body’s ability to sense where it is)
  • Extreme tiredness and fatigue

Often, people with hEDS have other symptoms:

  • Stretchy skin
  • Repeated joint dislocations
  • Anxiety disorders
  • Chronic pain
  • Gut issues
  • Postural orthostatic tachycardia syndrome (POTS) — a fast heart rate when they stand up
"Patients who come to their doctor with these symptoms can easily have attention and focus issues overlooked due to the acute nature of their complaints. It’s important to go through a comprehensive health assessment to receive proper diagnosis and treatment."
Dr. Michael Chichak
Medical provider at MEDvidi

Testing for Hypermobility

Doctors use the Beighton score[9] to test for generalized joint hypermobility. They do this by maneuvering various joints in different ways and measuring how far they move beyond normal. In adults, a score of 5 out of 9 or greater represents hypermobility. However, it’s not the only test your healthcare provider may recommend; it may be accompanied by skin assessment and an overview of medical history, ruling out other joint issues.

Importantly, some people just have extreme flexibility. It’s possible to have generalized joint hypermobility and no other symptoms. So, hypermobility can be harmless and not related to a specific diagnosis. If hypermobility doesn’t cause pain or joint instability and isn’t associated with hEDS or HSD, it usually doesn’t require specific treatment.

Why Are ADHD and Hypermobility Linked?

Although no specific cause or effect has been identified, there are a few ideas about the link between ADHD and hypermobility. 

Common Genetics

ADHD is a neurodevelopmental disorder, meaning it starts during brain development. One theory is that ADHD and hypermobility can be inherited together[6] : a single genetic factor affects neurological and connective tissue development.

Physical Symptoms Indirectly Cause Inattention

Often, people with ADHD and hypermobility also have physical symptoms[5] , as seen in hEDS:

Hypermobility-Associated TriggerPhysical Symptom

Poor proprioception

(the body’s ability to sense where it is)

Clumsiness

Autonomic nervous system problems

lead to dips in blood pressure

Dizziness, fainting, and fatigue
Connective tissue problems

Joint pain

Muscle pain

The theory is that these physical symptoms might affect[6] the brain’s cognitive (information-processing) function:

  • Because of poor proprioception, the brain is constantly trying to sense its position,which makes it harder to focus on thinking, learning, or planning.
  • A tired or dizzy brain doesn’t function well.
  • The brain concentrates on muscle and joint pain rather than the task it needs to do.
Get an individualized treatment plan and ongoing support for ADHD online.

ADHD Plus Joint Pain Point to Hypermobility

When people with ADHD have chronic pain or frequent joint pain, they are more likely to have hypermobility[5] . Reasons for muscle and joint pain include:

  • Joint instability leads to sprains and joint popping.
  • Posture and core muscle strength problems cause ADHD hypermobility-related back pain.
  • Clumsiness and poor coordination cause frequent injuries.
  • Fatigue, brain fog, dizziness, and low blood pressure lead to falls and injuries.

Getting Help If You Suspect Both ADHD and Hypermobility

If you are experiencing physical and cognitive challenges that are affecting your physical health, mental health, or overall well-being, you can start by visiting your primary care clinician.

Have a look through the following questions before your appointment. Having the answers will cover the bases and save time.

ADHD and Hypermobility Screening Questions

1. Do any of your immediate family members have ADHD or hypermobility conditions?

ADHD-related challenges:

2. Can you relate to any of the following statements?

  • Having poor attention to detail
  • Being easily distracted
  • Making careless mistakes
  • Focusing on anything is a challenge
  • Appearing not to listen when spoken to directly
  • Following instructions poorly
  • Trouble organizing or finishing tasks
  • Avoiding mentally demanding or boring tasks
  • Often losing keys, reading glasses, or mobile phones
  • Being forgetful about even routine daily activities
  • Feeling restless inside your body, or needing to move constantly
  • Being loud, talking too much, interrupting conversations, or blurting out answers
  • Difficulty waiting for your turn

Physical challenges:

3. Are any of your joints overly flexible? Which ones?

4. Do you have pain?

  1. Where?
  2. How often? Are there any triggers?
  3. For how long (weeks or years)?
  4. Do you take medication? What and how often?

5. Are you often tired, dizzy, or do you faint easily?

6. Are you clumsy or injury- or accident-prone?

This information will help your healthcare provider with diagnosis, treatment suggestions, and referrals.

"An accurate diagnosis of a hypermobility syndrome may involve additional blood work or consultation with a specialist such as an orthopedic doctor or rheumatologist. However, this can help guide the judgment of the ADHD treating doctor considering the correlation between hypermobility and ADHD."
Dr. Michael Chichak
Medical provider at MEDvidi

Combining Treatment Strategies for Hypermobility and ADHD

As we’ve shown, the cognitive and physical needs of hypermobility and ADHD often overlap and even make challenges worse. Therefore, treatment aims at managing symptoms of both. Here are a few things to keep in mind:

  • ADHD-specific treatment, consisting of talk therapy and medication, doesn’t help with hypermobility. 
  • Importantly, if hypermobility isn’t causing symptoms, such as pain, it usually doesn’t require specific treatment. When it is symptomatic, pain management strategies include physical therapy, medication, and sometimes orthopedic specialist opinions.

How Each Condition Can Affect the Other

Sleep

Sleep disorders and poor sleeping patterns are well-known coexisting conditions[10] with ADHD: ADHD causes sleep issues, and lack of sleep aggravates ADHD symptoms. Hypermobility-related pain can also interrupt sleep, escalating the existing vicious cycle.

Physical Activity

Getting enough physical exercise improves attention and focus[11] and reduces anxiety in people with ADHD. Joint pain will limit exercise, creating another vicious cycle.

ADHD Medications

ADHD medications[12] improve focus and support attention, activity levels, and information processing,

  • Stimulants, including amphetamine- and methylphenidate- based medications, are preferred first-line, when medications are deemed appropriate.
  • Non-stimulant options, such as atomoxetine or guanfacine, are usually considered when stimulants are dangerous to use or cause intolerable side effects. In coexisting hypermobility and ADHD, they might be used if there are POTS-like symptoms, palpitations, or blood pressure concerns.

Physical Therapy

Physical therapists help improve joint stability and reduce fall risks in the following ways:

  • “Strengthen” joints by building the muscle around them.
  • Teach people about the individual body’s limits, avoiding joint strain and injuries.
  • Help with posture and core muscle strength.
  • Improve proprioception by repeating sensory treatment challenges.
  • Treat POTS and orthostatic blood pressure dips[13] through exercise interventions.

As you can see, management of ADHD and coexisting hypermobility usually needs a team of healthcare professionals.

Hypermobility and ADHD: The Bottom Line

Recent evidence shows a connection between hypermobility and ADHD. Each condition presents its own challenges, and together they may impact daily life even more. If they coexist, management needs to address both; therefore, an accurate diagnosis is essential.

If you suspect you have combined hypermobility and ADHD, you can book an online appointment for ADHD assessment and treatment and discuss the possibility with the MEDvidi team.

FAQs

ADHD is associated with[5] joint pain in some people, but doesn’t directly cause it.

ADHD is associated with[5] muscle and joint issues in some people, but doesn’t directly cause them.

Generalized joint hypermobility and ADHD in women appear to be more commonly associated[5] than in men with ADHD, although the study evidence refers to all neurodivergent conditions.

There is an association[6] between hypermobile Ehlers-Danlos syndrome and ADHD; however, having one doesn’t automatically mean you will have the other.

Around 50%[5] of individuals diagnosed with ADHD have generalized joint hypermobility.

No, having hypermobility doesn’t mean you have ADHD. Although there is an association between hypermobility and ADHD, ADHD is diagnosed with specific criteria reflecting symptoms of inattention, hyperactivity, and impulsivity.

Sources

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13 sources
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  2. Carroll MB. Hypermobility spectrum disorders: A review. Rheumatol Immunol Res. 2023 Jul 22
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  3. Magnus W, Anilkumar AC, Shaban K. Attention Deficit Hyperactivity Disorder. [Updated 2023 Aug 8]
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  4. Glans M, Thelin N, Humble MB, Elwin M, Bejerot S. Association between adult attention-deficit hyperactivity disorder and generalised joint hypermobility: A cross-sectional case control comparison. Journal of Psychiatric Research2021
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  5. Csecs JLL, Iodice V, Rae CL, Brooke A, Simmons R, Quadt L, Savage GK, Dowell NG, Prowse F, Themelis K, Mathias CJ, Critchley HD, Eccles JA. Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain. Front Psychiatry. 2022 Feb 2
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  6. Kindgren E, Quiñones Perez A, Knez R. Prevalence of ADHD and Autism Spectrum Disorder in Children with Hypermobility Spectrum Disorders or Hypermobile Ehlers-Danlos Syndrome: A Retrospective Study. Neuropsychiatr Dis Treat. 2021 Feb 10
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  7. Csecs JLL, Iodice V, Rae CL, Brooke A, Simmons R, Quadt L, Savage GK, Dowell NG, Prowse F, Themelis K, Mathias CJ, Critchley HD, Eccles JA. Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain. Front Psychiatry. 2022 Feb 2
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  8. Yew KS, Kamps-Schmitt KA, Borge R. Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders. American Family Physician2021
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  9. Malek S, Reinhold EJ, Pearce GS. The Beighton Score as a measure of generalised joint hypermobility. Rheumatol Int. 2021 Oct
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  10. Hvolby A. Associations of Sleep Disturbance with ADHD: Implications for Treatment. ADHD Attention Deficit and Hyperactivity Disorders2014
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  11. Rassovsky Y, Alfassi T. Attention Improves During Physical Exercise in Individuals With ADHD. Front Psychol. 2019 Jan 9
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  12. Attention-Deficit/Hyperactivity Disorder Medications for Adults: Drugs [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2024 Nov
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  13. Gonçalves Leite Rocco P, Reategui-Rivera CM, Finkelstein J. Exercise Interventions in the Management of Postural Orthostatic Tachycardia Syndrome: A Scoping Review. J Multidiscip Healthc. 2024 Dec 9
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Dorianne Green
Author
Dorianne Green
Medical Writer
Dr. Michael Chichak
Medical Reviewer
Dr. Michael Chichak
MD
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