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How Does Online Trazodone (Desyrel) Prescription Work

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Start a holistic mental health journey at MEDvidi. Discuss the use of Trazodone for depression, anxiety, PTSD, or insomnia and receive a prescription online if deemed necessary.
Written by:

Wafaa Amjad Dar

Medical Disclaimer
The medications listed on this website are provided for informational purposes only. Their inclusion does not guarantee that they will be prescribed to any individual, as treatment decisions are ultimately at the discretion of healthcare providers. This list is not exhaustive, and healthcare providers may prescribe other medications, including non-stimulant options, based on the patient’s unique health circumstances and needs. Read more

In an era defined by digital convenience and accessibility, many people with mental health conditions like depression and anxiety can use online prescription services. After a detailed video consultation, licensed healthcare providers can prescribe medications if deemed necessary. One of them that can be selected for various issues is Desyrel (trazodone). Below, let’s review its common uses, advantages, and side effects. You will also learn more about the cases when trazodone can and cannot be prescribed online.

Connect with a medical expert online to learn more about treatments for depression and anxiety.

What Is Trazodone?

Trazodone, sold under the brand name Desyrel, is an FDA-approved [1*] antidepressant medication categorized as a serotonin antagonist and reuptake inhibitor (SARI). Its mechanism of action [2*] involves two key elements: blocking serotonin from binding to its receptors and inhibiting its reuptake. By doing so, trazodone elevates levels of serotonin in the brain, which contributes to improved mood, sense of calm, and better sleep.

Trazodone Uses

Trazodone is FDA-approved for major depressive disorder (MDD [3*] ). It can also be prescribed off-label to treat insomnia [4*] , obstructive sleep apnea [5*] , and anxiety [6*] , and it can be helpful for people with post-traumatic stress disorder [7*] (PTSD) who have nightmares or other sleep problems.

The use of trazodone is contingent upon dosage, as its effects are dose-dependent. At lower doses, around 50 mg, trazodone primarily acts as an insomnia medication, while higher doses ranging from 150 mg to 300 mg are used to treat depression. Note that the exact suitable dosage is determined by a healthcare professional in each particular case, and it’s important to follow the instructions.

When clinicians can prescribe trazodone

Does Trazodone Require a Prescription?

Trazodone requires a prescription from a licensed healthcare professional. It is due to it having a potential for side effects and possible drug interactions. Your healthcare provider will conduct a comprehensive evaluation to determine if Trazodone is suitable for your specific condition. If it deems suitable they will provide a tailored prescription, including the appropriate dosage. Obtaining trazodone without a prescription is both unsafe and against the law.

Who Can Prescribe Trazodone?

Trazodone must be prescribed by a licensed medical provider. In the United States, medical professionals authorized to prescribe trazodone include Medical Doctors (MD), Psychiatrists, Primary Care Physicians, Physician Assistants (PA), Nurse Practitioners (NP), and Neurologists, among others. Note that the list of providers may slightly vary by state due to local laws and regulations.

Can Trazodone Be Prescribed Online?

Prescribing guidelines and regulations may vary per state, but generally, patients can get trazodone prescribed online. To discuss this option and obtain a prescription online, you should have a video appointment with a licensed healthcare provider. They will conduct a comprehensive assessment of your symptoms, provide a diagnosis, and, if deemed appropriate for your condition, prescribe trazodone or another medication.

Note that booking an appointment doesn’t guarantee receiving a prescription because the decision is based on an assessment of symptoms and other aspects.

Obtaining a Trazodone Prescription Online at MEDvidi

Healthcare professionals at MEDvidi are certified to prescribe medication online, including trazodone. It can be prescribed to treat insomnia, anxiety, and depression. To discuss whether it is a suitable treatment option in your particular case, follow the next steps:

  • Create your account on MEDvidi and fill out the basic information.
  • Schedule an appointment at a convenient time slot.
  • During an online video consultation, a medical professional will assess your symptoms, make a diagnosis, and create a treatment plan for you. This is also an opportunity for you to openly discuss your questions and address any concerns you may have.
  • If your healthcare professional thinks trazodone is appropriate for you, they will provide you with a prescription. It will be sent digitally to a local pharmacy of your choice.
  • Schedule follow-up appointments to discuss trazodone refills or treatment adjustments.
Consult a healthcare expert online to receive personalized support and treatment for anxiety or depression.

Side Effects of Desyrel (Trazodone)

Desyrel, like all antidepressants, can cause side effects. In different people, they can vary in frequency and severity. Some common side effects are the following:

  • Blood pressure changes
  • Dizziness
  • Drowsiness
  • Dry mouth 
  • Headache
  • Blurred vision 
  • Nausea
  • Bad taste
  • Constipation 
  • Irregular heartbeat
  • Decreased sexual desire
  • Itchy eyes ringing

It’s important to note that not everyone taking trazodone will experience these side effects, and these adverse reactions may disappear on their own within several days. However, if you experience severe or prolonged side effects, consider consulting with a healthcare professional.

Pros and cons of trazodone

Contraindications and Precautions

While trazodone can be highly effective in treating depression and anxiety, in some cases, patients should exercise caution or avoid taking it. These include:

  • Previous allergic reaction to trazodone or any of its components.
  • Concurrent use with monoamine oxidase inhibitors (MAOIs), or within 14 days of discontinuing MAOIs due to the risk of serotonin syndrome, a potentially life-threatening condition.
  • There may be a risk of irregular heartbeats and chest pain, so those who recently had a heart attack should discuss it with a healthcare provider.
  • When used in combination with blood thinners like aspirin, NSAIDs, or warfarin, there may be an increased risk of unusual bleeding.
  • It’s advisable to undergo screening for bipolar disorder to prevent the risk of mania.
  • Trazodone may impair your motor skills, so avoid operating machinery until you understand how this medication affects you.
  • People taking other central nervous system (CNS) depressants, such as alcoholic beverages or muscle relaxants, should be mindful of potential interactions.
  • Avoid combining with herbal products like St. John’s Wort or tryptophan.
  • Don’t stand up too quickly from a sitting or lying position since trazodone may cause drowsiness.
  • If you experience new or worsening depression, suicidal thoughts, panic attacks, aggressive behavior, irritability, severe restlessness, or any concerning symptoms, inform your clinician immediately.

Do not suddenly stop taking trazodone, always consult your healthcare provider for guidance on the tapering approach to avoid withdrawal symptoms.

Contact us today to schedule a video visit and get personalized guidance on depression treatment.

Bottom Line

MEDvidi offers a reliable and accessible way to obtain online prescriptions when necessary for mental health treatment. Our dedicated healthcare professionals are here to assess your symptoms and provide a detailed plan for you to treat depression, anxiety, or another condition. They are certified to prescribe medication online, including trazodone, and can consult you on self-help activities that can enhance its effects.


Trazodone is considered to have a lower risk of addiction or dependence compared to some other medications. It’s not classified as a controlled substance. Still, any medication, including trazodone, can be misused or lead to dependence if not taken as directed. To reduce these risks, always follow your clinician’s guidance.
No, trazodone is a prescription medication and is not available over the counter. It can only be obtained with a valid prescription from a licensed healthcare professional.
Yes, it is legal to buy trazodone with a valid prescription from a licensed healthcare practitioner. To ensure safety, obtain medicines from a reputable, licensed online pharmacy.


7 sources
  1. Desyrel (trazodone hydrochloride) tablets
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  2. Mechanism of Action of Trazodone: a Multifunctional Drug
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  3. Rediscovering Trazodone for the Treatment of Major Depressive Disorder
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  4. Trazodone for Insomnia: A Systematic Review
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  5. Trazodone Effects on Obstructive Sleep Apnea and Non-REM Arousal Threshold
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  6. Antidepressants for the treatment of generalized anxiety disorder. A placebo-controlled comparison of imipramine, trazodone, and diazepam
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  7. Survey on the usefulness of trazodone in patients with PTSD with insomnia or nightmares
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Written by:

Wafaa Amjad Dar

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Written by:

Wafaa Amjad Dar



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Evidence Based

This article is based on scientific evidence, written by experts and fact checked by experts.

Our team of experts strive to be objective, unbiased, honest and to present both sides of the argument.

This article contains scientific references. The numbers
in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers.