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Farmapram (Alprazolam): Uses, Warnings & Side Effects

Zach Reale
Written by:
Zach Reale
PharmD
Dr. Henry Bradford
Medical Reviewer:
Dr. Henry Bradford
MD

Farmapram is the brand name of the medication alprazolam marketed and approved for use in Mexico. In the US, the brand name is Xanax. This article will cover the uses, safety, and risks of using alprazolam in the US. It will also address the safety of using Farmapram obtained either in Mexico or the US.

Highlights

  • Farmapram is the name of a medication available in Mexico with the active ingredient alprazolam, just like Xanax in the US.
  • Farmapram, or alprazolam, is a benzodiazepine. This class of medications has significant risks of abuse and misuse and can be obtained only by prescription. Only obtain the medication through official sources and with the use of proper prescriptions. 
  • Farmapram has significant drug interactions with other medications. Check with your healthcare provider about all possible interactions. 
  • Treatment with Farmapram should be closely monitored. Starting and stopping alprazolam use must be done slowly and gradually to reduce the risk of severe side effects or withdrawal reactions. Never change doses without the direction of a healthcare professional.

What Is Farmapram (Alprazolam)?

Alprazolam is a benzodiazepine medication that acts on the central nervous system (CNS) to reduce symptoms of anxiety and panic disorder[1] . Alprazolam acts on specific receptors in the CNS called GABA receptors to reduce their activity. Since the receptors are responsible for symptoms of anxiety, the reduction of their activity leads to a decrease in symptoms.

In the US, alprazolam is FDA-approved[2] for acute (or short-term) treatment of generalized anxiety disorder in adults and panic disorder in adults. When a healthcare provider decides to prescribe alprazolam for other conditions, it is considered ‘off-label use’. This type of use should be done cautiously, and always under the supervision of a healthcare provider.

See a medical provider online to learn if you have an anxiety disorder and get personalized treatment.

Farmapram vs. Xanax: Key Differences and Similarities

Both Farmapram and Xanax[2] are brand-name products for alprazolam. Farmapram is manufactured by IFA Celtics for use in Mexico, and Xanax is manufactured by Pfizer for use in the US. There are also numerous generic versions of alprazolam approved and manufactured for use in the US. It is important to note that while the active ingredient of both is the same, other ingredients may differ between the two formulations causing different effects or even differing risks of allergies.

An important reminder: the FDA only regulates medication for sale and use in the US. If attempting to purchase medication outside of the US, you may be at an increased risk for counterfeit or imitation medications that could be dangerous. While it may be tempting because of lower costs and reduced barriers, there is a risk of serious harm[3] or death if medication is not what it is stated to be. There have been reports of counterfeit medications sold to tourists specifically in high-tourism areas of Mexico.

"Alprazolam is a high-potency, fast-acting benzodiazepine commonly used to treat anxiety symptoms, particularly panic attacks. While it has a rapid onset, its effects typically last only a few hours. In cases where a benzodiazepine is indicated, a longer-acting alternative, such as lorazepam, may be preferred for more sustained relief. Consult your healthcare provider to receive a personalized treatment plan."
Dr. Henry Bradford, MD
Medical provider at MEDvidi

Is Farmapram FDA-approved? Legality and Regulations

Farmapram is not FDA-approved in the US.

Only brand name Xanax or approved generic forms of alprazolam are FDA-approved in the US. The active ingredient alprazolam is a controlled substance in the US and is highly regulated[4] . You should only obtain alprazolam or Xanax from a licensed pharmacy or facility with a prescription from a qualified healthcare provider.

You should not travel with controlled substances unless absolutely necessary. If traveling with alprazolam, you should carry it in the legally compliant vial it was dispensed to you in, and the name on the vial should match a form of identification. Additionally, you should check the local laws about having alprazolam in your possession and traveling with it. Finally, you should not attempt to purchase Farmapram online, or have the medication shipped to you, especially across country borders. While it is legal to mail certain medications within the US, it must be from a pharmacy to a patient, in accordance with local laws of both the sending and receiving state, and only with a legal prescription.

The FDA and DEA coordinate[5] the bringing of controlled substances across borders for personal use. Decisions are made on a case-by-case basis and require proper paperwork and ensuring that not more than a 90-day supply of medication is brought along. In this case, there may be a legal way to bring Farmapram back to the US, but only if legally obtained, legally carried, and legally declared to officials.

What Does Farmapram Look Like?

Farmapram manufactured by IFA Celtics for use in Mexico is available as four different pills. Knowing their look and identifying markings can help ensure you are actually receiving Farmapram. 

It is always best to receive the medication in its original packaging. Look for signs of an official product like a lot number, an expiration date, and a phone number of the manufacturer. Descriptions of tablets are located below:

  • White, oval 0.25 mg tablets with a score (or break line) on one side and ‘IFA’ imprinted on the other side.
  • Blue, oval 0.5 mg tablets with a score (or break line) on one side and ‘IFA’ imprinted on the other side.
  • Light purple, oval 1 mg tablets with a score (or break line) on one side and ‘IFA’ imprinted on the other side.
  • White, rectangular 2 mg tablets, known as bars, with three scores (or break lines) on one side and two scores on the other side.

Farmapram Dosages

The available doses of Farmapram are listed above with descriptions. The approved dosages for alprazolam (Xanax) use in the US are clearly defined by the FDA[6] . They vary by what alprazolam is being used to treat. A general guide for doses of alprazolam is to use the lowest possible effective dose, and regularly reevaluate the need for its use.

When alprazolam is used for generalized anxiety disorder, the recommended starting dose[2] is 0.25 mg to 0.5 mg taken up to three times daily. Throughout the first days and weeks of treatment, your provider may direct you to increase your dose or frequency of use. The typical maximum dose of alprazolam used for anxiety is 4 mg total in one day, divided into multiple doses.

When used for panic disorder, the recommended starting dose[2] is 0.5 mg up to three times daily. Depending on the response to treatment, your healthcare provider may increase your dose. While trials showed that some patients required up to 10 mg per day in divided doses, follow-up studies have demonstrated that doses above 4 mg per day are rarely required. If you are taking more than 4 mg in a day you should see your provider consistently and only take higher doses if absolutely necessary. Never exceed the dose prescribed to you by a medical professional.

Sometimes, alprazolam is used for other conditions, and the doses may vary. This type of use is considered off-label and it should only happen at the direction of a licensed US-based healthcare provider. They should be able to explain their reasoning for your treatment and dose.

Have a mental health assessment online and receive an individualized treatment plan for anxiety.

Farmapram Side Effects

Taking Farmapram, or alprazolam, can put you at risk of many side effects, some common and less serious, and some severe. Any side effect should be reported to and addressed by your provider. If you feel your life is in danger, call 911 immediately and seek care. 

Below are lists of some of the most common side effects[2] experienced by those taking alprazolam and the most important serious side effects to be aware of. It is not a comprehensive list and you should discuss side effect risk at length with your healthcare provider.

Common side effects:

  • Drowsiness
  • Dizziness
  • Akathisia
  • Light-headedness
  • Dry mouth
  • Increased salivation
  • Low blood pressure
  • Fatigue
  • Impaired coordination
  • Confusion
  • Changes in libido
  • Constipation

Severe side effects:

  • Central nervous system depression
  • Abuse, misuse, and addiction
  • Dependence and withdrawal reactions
  • Worsening depression 
  • Episodes of mania or hypomania
  • Respiratory depression

Risks and Dangers

Due to the specific risks[7] when taking Farmapram or alprazolam, there are certain people who should not take the medication, or use it very cautiously.

The following list consists of severe conditions and specific groups that may be at a higher risk. If any of these apply to you, be sure to bring it up with your healthcare provider to ensure your safe use. They may decide alprazolam is not right for you, or change your dosing to make treatment safer.

  • Risk of use with opioids. Taking any benzodiazepine, including alprazolam, along with opioids can greatly increase the risk of respiratory depression, coma, and death. If you also take opioids you should use the lowest dose possible of each and be constantly monitored for signs of sedation. Talk to your prescriber about carrying Naloxone as well for emergency use in the case of an overdose. 
  • Abuse, misuse, and addiction. All benzodiazepines carry a risk for abuse and addiction that can lead to death. This risk increases when doses taken are above the prescribed dose, or used with other medications, drugs, or alcohol. If you have a history of substance abuse, discuss it with your prescriber. 
  • Central nervous depression. Alprazolam and all benzodiazepines[8] reduce a person’s alertness, and this can be dangerous for those driving, or operating heavy machinery. Discuss with your prescriber the best time to take alprazolam, and be sure you know how the medication affects you before resuming normal work. 
  • Worsening depression. Alprazolam has been shown to worsen depression. If you have depression be sure to alert your healthcare provider of your alprazolam treatment and monitor for signs of worsening depression.
  • Episodes of mania. Patients with mania or a history of manic episodes should use alprazolam cautiously as there have been reports of mania and hypomania developing when patients are taking alprazolam. 
  • Decreased respiratory function. If you have a lung disease or have impaired lung function, you should discuss with your doctor safe treatment. There is evidence of an increased risk of adverse outcomes among those with COPD; also, benzodiazepines are a risk factor[9] for respiratory failure in patients with COPD.


There are also many medications that can interact with alprazolam[2] . These interactions can be dangerous and harmful or also cause either medication to not work as well as intended. You should always disclose all medications you take to your healthcare provider. Be sure to share information about prescription medications, over-the-counter products, vitamins and supplements, and especially alcohol, tobacco, marijuana or illicit drugs.

"Benzodiazepines carry a high risk of tolerance and dependence, which is why they are typically prescribed for short-term use. It is important to inform your healthcare provider of all other medications you are taking, as combining benzodiazepines with other central nervous system depressants — such as opioids or sleep aids — can significantly increase the risk of serious side effects."
Dr. Henry Bradford, MD
Medical provider at MEDvidi

Below is a list of some important interactions to note. Discuss at length all of your medications with a pharmacist or member of your healthcare team:

  • Alprazolam should not be taken with medications that strongly inhibit a liver enzyme called CYP3A. Examples of these medications include ketoconazole, itraconazole, fluvoxamine, and cimetidine.
  • Opioids should be avoided if possible, due to the risk of CNS depression.
  • CNS depressants should be avoided and used sparingly. Examples include antihistamines, seizure medications, alcohol, and psychotropic medications.
  • Digoxin, a medication used for heart failure, when combined with alprazolam can rise to dangerous levels in the body. Patients taking digoxin and alprazolam should be monitored closely and adjust doses of both if necessary.

See the full list of alprazolam drug interactions, including over-the-counter and herbal products, in our dedicated article.

Addiction, Dependence, and Withdrawal

Alprazolam is a unique benzodiazepine as it is one of the most potent, the most widely prescribed[10] , and can produce withdrawal symptoms after only a few weeks of use. Dependence happens because the central nervous system changes and adapts to the continued use of alprazolam. 

When the dose is decreased or stopped altogether in patients with dependence, they can experience withdrawal symptoms. For this reason, it is strongly recommended that when stopping treatment with alprazolam, you should decrease very slowly over time, always at the direction of a healthcare professional. 

Withdrawal symptoms include:

  • Panic attacks
  • Anxiety
  • Insomnia
  • Fast heartbeat
  • Dizziness
  • Nightmares
  • Delirium

Farmapram, or alprazolam, has a high risk of addiction, misuse, and abuse. Patients that have a history of substance use disorder or addiction, should use alprazolam cautiously and under close supervision by a healthcare professional. Addiction[11] is a complex disease state that occurs when the body develops a dependence where people compulsively seek and use drugs despite harmful consequences.


If you feel you are craving alprazolam and need it but don’t feel symptoms of panic or anxiety, or if you feel you are using it too frequently, seek help immediately. Do not attempt any treatment on your own as it can make the situation worse or life-threatening. Your healthcare provider may recommend you seek specific addiction treatment to help obtain effective management strategies. Studies[12] show that a combination of medication to treat addiction combined with behavioral therapy is often the best chance of success.

Safer Alternatives for Anxiety Management

Farmapram, or alprazolam, is not the only option for treating and managing anxiety. A large meta-analysis reviewing non-medication treatments for anxiety[13] found that physical activity, improved nutrition, and psychoeducation all improved anxiety symptoms. It is important to note that lifestyle changes are not always effective on their own, but many offer significant benefits when combined with medication therapy and/or behavioral or talk therapy.

There are also many other anti-anxiety medications available as prescription treatments. Specifically, the use of non-benzodiazepines could be considered a safer alternative. Non-benzo medications often have less abuse potential and less risk of central nervous depression. If you are uncomfortable taking alprazolam, speak with your provider about alternative options.

Conclusion

If you think treatment with Farmapram may be right for you, speak to a licensed healthcare professional in your state or country. In the US, you will likely be prescribed alprazolam instead of Farmapram. Do not seek out medication, especially controlled substances like alprazolam from unlicensed sources. 

If you do not have a healthcare provider you can always connect with the MEDvidi team for online anxiety treatment.

Frequently Asked Questions

Both products have the same active ingredient alprazolam. Farmapram is marketed and sold in Mexico, but Xanax is marketed and sold in the US. Farmapram is not FDA-approved or recommended for those living in the US or seeking care in the US.

Farmapram is only safe if used appropriately under the supervision of a licensed healthcare professional. There have been reports of unsafe imitation medication made to look like Farmapram. It is also unsafe to obtain Farmapram without a prescription from a licensed healthcare provider.

Farmapram or alprazolam works soon after taking a dose. Most patients feel the effects of the medication within an hour. Alprazolam is only approved for short-term treatment and should not be used long-term or longer than required.

One dose of Farmapram or alprazolam lasts between 4 to 6 hours. This is the main reason why most treatments with alprazolam require multiple doses throughout the day. Be sure to keep track of each dose you take ensuring you do not take too many or too few doses.

Sources

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13 sources
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  3. Casner PR, Guerra LG. Purchasing prescription medication in Mexico without a prescription. The experience at the border. Western Journal of Medicine. 1992;156(5):512. Accessed June 10, 2025.
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  4. Ortiz NR, Preuss CV. Controlled Substance Act. StatPearls Publishing; 2021.
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  5. Affairs O of R. Personal Importation. FDA. Published online May 7, 2019.
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  9. Chen SJ, Yeh CM, Chao TF, et al. The Use of Benzodiazepine Receptor Agonists and Risk of Respiratory Failure in Patients with Chronic Obstructive Pulmonary Disease: A Nationwide Population-Based Case-Control Study. Sleep. 2015;38(7):1045-1050.
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  10. Ait-Daoud N, Hamby AS, Sharma S, Blevins D. A Review of Alprazolam Use, Misuse, and Withdrawal. Journal of Addiction Medicine.
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  11. National Institute on Drug Abuse. Understanding Drug Use and Addiction Drug Facts. National Institute on Drug Abuse. Published 2018.
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  12. Ray LA, Meredith LR, Kiluk BD, Walthers J, Carroll KM, Magill M. Combined Pharmacotherapy and Cognitive Behavioral Therapy for Adults With Alcohol or Substance Use Disorders. JAMA Network Open. 2020;3(6).
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  13. Amiri S, Mahmood N, Javaid SF, Khan MA. The Effect of Lifestyle Interventions on Anxiety, Depression and Stress: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Healthcare. 2024;12(22):2263-2263.
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Zach Reale
Written by:
Zach Reale
PharmD
Dr. Henry Bradford
Medical Reviewer:
Dr. Henry Bradford
MD
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