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How Long Does It Take for Lexapro to Work?

Written by:
Rabia Khaliq
MSc in Applied Psychology
Reviewer:
Dr. Bradley Noon
MD
Medical Disclaimer
The medications listed on this website are provided for informational purposes only. Their inclusion does not guarantee that they will be prescribed to any individual, as treatment decisions are ultimately at the discretion of healthcare providers. This list is not exhaustive, and healthcare providers may prescribe other medications, including non-stimulant options, based on the patient’s unique health circumstances and needs. Read more

Highlights

  • Lexapro (escitalopram) belongs to the SSRI (selective serotonin reuptake inhibitor) class of medication.
  • Lexapro raises serotonin levels in the brain, aiding mood regulation and reducing the symptoms of anxiety and depression.
  • Initial improvement can be noticed after the first two weeks while significant improvement may take up to three months.
  • If you feel that Lexapro is not working for several weeks or if you experience severe side effects, speak with your healthcare provider.

Lexapro (escitalopram) is an FDA-approved [1*] and widely used antidepressant medication. It belongs to the class of selective serotonin reuptake inhibitors (SSRIs) that block serotonin reuptake in the brain, improving mood and promoting relaxation.

It takes time for Lexapro to work because it has to build up in your system. So, how long can it take, how to know if Lexapro is working, and when it’s time to ask your doctor about alternative treatment? Read on as all this is discussed below.

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What Is Lexapro?

Lexapro works by balancing neurotransmitters in the brain, particularly serotonin. Normally, there is an adequate amount of neurotransmitters that deliver information to the cells and then get reabsorbed into neurons [2*] . This process is called reuptake.

At the same time, depression and some other mental health conditions are associated with serotonin imbalances. So, medications like Lexapro slow down the reuptake process to raise the amount of available serotonin in the brain. Ultimately, this helps improve mood and reduce the symptoms of depression, generalized anxiety disorder, obsessive-compulsive disorder (OCD), and some others.

How Long Does Lexapro Take to Work for Different Symptoms and Conditions?

Lexapro can be used to treat depression and anxiety disorders, promoting better concentration and overall cognitive performance. The time it takes for Lexapro to impart its therapeutic effects may vary across different mental conditions:

  • Depression: Improvements in appetite, energy, and sleep patterns can be observed [3*] in patients with major depressive disorder within the first or second week of treatment.
  • Generalized Anxiety Disorder: Lexapro typically takes about two to four weeks to address anxiety symptoms.
  • Panic Disorder: Studies [4*] suggest significant symptom improvement for panic disorder from the fourth week of Lexapro use. It focuses on reducing excessive anxiety, a key factor in panic attacks.
  • Obsessive-compulsive Disorder (OCD): Lexapro is occasionally prescribed for OCD. Studies show that its impact on OCD symptoms may become evident [5*] around the fourth week of treatment.

Note that these time spans may differ from person to person. Consult your healthcare provider if you think your treatment plan should be modified.

How to Know If Lexapro Is Working

According to studies [6*] , escitalopram shows significant symptom improvement compared to a placebo group within the first and second weeks of treatment. Aside from recognized efficacy, it also means that the effects of Lexapro are not immediate. When taking Lexapro, you may not observe improvement for a few weeks. In case of a delay, do not increase the dose but consult your clinician. They will tell you if you still have to wait for the effect or adjust your treatment plan.

When Lexapro starts working, you can feel a gradual relief from your symptoms. These include a more positive mood, decreased pessimistic and suicidal thoughts, improved sleep quality, enhanced concentration, and more. It may take a while for you to get used to the new mental state as serotonin is released in the brain.

Book an appointment with a healthcare professional and receive a prescription online if deemed necessary.

When Does Lexapro Peak in Your System

Like other medications belonging to the class of antidepressants, Lexapro takes time to achieve its complete therapeutic efficacy. This medication works on a molecular level in the brain, which is an intricate process that needs time to unfold and stabilize. Therefore, it’s important to adhere consistently to the prescribed medication regimen to attain the intended outcomes. It may take about 6-8 weeks to get the full benefits of a Lexapro treatment.

What Can Affect the Effectiveness of Lexapro

Lexapro might work faster or slower than usual because of the following factors:

  • Individual body chemistry
  • Other medical conditions
  • Drug interactions

Always consult with your healthcare provider on pre-existing conditions and other medications you are taking to get appropriate treatment.

How Does Lexapro Make You Feel: The Timeline

Lexapro may work differently, depending on the various individual factors. However, here’s an overview of this medication’s general timeline.

Initial days

  • Right after starting Lexapro you may experience a few common side effects, such as headaches, nausea, exhaustion, and trouble sleeping. Some individuals may also feel an increase in anxiety. 
  • The improvements in mood and anxiety might not be noticed immediately. Take the medication as prescribed, even if you don’t feel better right away.

First week or two weeks

  • While side effects are possible, they usually lessen as your body adjusts to the medication.
  • At this stage, some people may see mild improvements in their mood or anxiety, but significant changes are usually not noticeable.

By two months

  • Many people start to see a noticeable improvement in their symptoms of anxiety or depression by this point. The full therapeutic benefits of Lexapro are most likely to become apparent during this time.
  • Often, the initial adverse effects go away or get easier to handle. While side effects are still possible for certain people, for example, slight weight gain, they are usually not as disturbing as during the first days.

Beyond two months

  • Most people whose symptoms improve while using Lexapro for anxiety or depression will continue to experience these benefits. It’s typical to have reduced anxiety and depression along with a more constant and steady mood.
  • Some people may continue to experience minor side effects. If you have long-lasting or severe adverse effects, discuss it with your mental health professional.

It’s important to keep taking the medication as directed and keep in touch with your clinician to track your health dynamics and discuss possible side effects or withdrawal symptoms (if considering stopping the medication).

What to Do If You Think Lexapro Is Not Working

Although it may take time for Lexapro to work, you should start noticing improvement in symptoms in a few weeks. If there are no positive effects after this period or you experience severe adverse reactions, consult with your doctor. They will tell you if you have to wait, prescribe another Lexapro dosage, or switch to another medication.

Sometimes, combining medication management with psychotherapy, such as cognitive-behavioral therapy, can increase treatment efficacy. Other supporting practices include a balanced diet, regular exercise, sufficient sleep, and stress reduction. It’s important to communicate openly with your healthcare practitioner during your Lexapro therapy to monitor its effects and learn how to improve them.

Related: Signs Your Antidepressant Has Stopped Working

Effects of Xanax According to Dosage

Xanax is available in 0.25 mg, 0.5 mg, 1 mg, and 2 mg dosages. As the dose rises, the effects become more prominent, from mild anxiety relief to strong sedation. Doctors generally advise to start with the lowest dose and then increase it if necessary.

Conclusion

Lexapro can help in managing an anxiety disorder and depression but its effects are not immediate. Also, it may cause side effects, so it is essential to follow the given instructions and be in touch with your clinician.

At MEDvidi, you can receive a personalized treatment plan for depression or anxiety online. A qualified healthcare practitioner will assess your symptoms and health history and offer treatment tailored to your circumstances.

Frequently Asked Questions

Lexapro enhances the brain’s biochemistry to help a person deal with mental health issues, but it takes time for the neurotransmitters and receptors to adapt to these alterations. Relief from symptoms usually happens gradually within several weeks as the body adjusts to the medication.

Although Lexapro may quickly affect serotonin levels, it usually takes four to six weeks for mood and anxiety to improve significantly.
Your mood may start to improve, your sense of hopelessness or depression lessens, and anxiety levels noticeably decrease, with fewer instances of worry or fear. As Lexapro starts to work, people also frequently report better sleep patterns.
Take Lexapro at the same time every day to keep its level constant in your bloodstream. Depending on Lexapro’s effect on sleep, you can take it in the morning or at night.
The duration of treatment depends on the condition and individual response to the medication. Continuing treatment over time is important for maintaining symptom relief and preventing relapse. Regular evaluations with your healthcare provider are crucial to determine the best course of action.

Sources

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6 sources
  1. Lexapro
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  2. Selective Serotonin Reuptake Inhibitors
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  3. Escitalopram for the management of major depressive disorder: a review of its efficacy, safety, and patient acceptability
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  4. The therapeutic potential of escitalopram in the treatment of panic disorder
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  5. Escitalopram in obsessive-compulsive disorder: a randomized, placebo-controlled, paroxetine-referenced, fixed-dose, 24-week study
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  6. Escitalopram 10 mg/day is effective and well tolerated in a placebo-controlled study in depression in primary care
    Source link
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Written by:
Rabia Khaliq
MSc in Applied Psychology
Reviewer:
Dr. Bradley Noon
MD
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This article is based on scientific evidence, written by experts and fact checked by experts.

Our team of experts strive to be objective, unbiased, honest and to present both sides of the argument.

This article contains scientific references. The numbers
in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers.