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How to Get a Cymbalta (Duloxetine) Prescription Online

FDA approved
See a healthcare provider online to receive help for anxiety or depression from home and get Cymbalta prescribed online, if appropriate.
Same-day appointments available
HSA & FSA accepted
Insurance is not needed
Online prescription, if clinically appropriate
Jessica Men
Author:
Jessica Men
PharmD
Christina Bookwalter
Medical Reviewer:
Christina Bookwalter
PharmD
The medications listed on this website are provided for informational purposes only.
Their inclusion does not guarantee they will be prescribed to any individual, as treatment decisions are ultimately at the discretion of healthcare providers. Healthcare providers may prescribe other medications or recommend non-pharmacological treatment based on the patient’s unique health circumstances and needs. Read more

Cymbalta has a boxed warning[1] , the most serious type of warning from the Food and Drug Administration (FDA). Cymbalta has a risk of suicidal thoughts and behavior with antidepressant use in patients over age 24. Remember to discuss the risks with your healthcare provider.

Highlights

  • Cymbalta (duloxetine) is a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant approved to treat depression and anxiety disorders.
  • Cymbalta has specific side effects and risks. Remember to discuss them with your healthcare provider before starting treatment.
  • MEDvidi has licensed healthcare providers in several states who are able to prescribe Cymbalta if deemed clinically necessary.

Depression and anxiety are conditions that many adults struggle with today. As someone with depression, you may experience constant sadness, a loss of interest in your usual activities, and changes in sleep, appetite, and energy levels. Anxiety may cause excessive worry, difficulty concentrating, irritability, or trouble sleeping. Often, these symptoms can interrupt and become detrimental to regular life.

The process of getting treated for anxiety or depression is manageable, including online medication management. Read on to find out if duloxetine may be a suitable option for you and how to get duloxetine (Cymbalta) prescribed online.

See a healthcare provider to find out what treatment option is optimal for you and receive a prescription online.

What Is Cymbalta (Duloxetine)?

Cymbalta (duloxetine)[2] is a type of antidepressant known as a serotonin and norepinephrine reuptake inhibitor (SNRI). It is approved by the FDA to treat several conditions, including major depressive disorder (MDD), generalized anxiety disorder (GAD), fibromyalgia, chronic musculoskeletal pain, and diabetic peripheral neuropathy.

As an SNRI, Cymbalta is thought to work for depression and anxiety because it increases the level of serotonin and norepinephrine in the brain (by blocking their reuptake back into nerves). In addition to these general SNRI properties, Cymbalta also increases dopamine levels in the prefrontal cortex; when this brain region is underactive, it contributes to depression, so the actions of Cymbalta contribute to the efficacy of treatment[3] . By increasing the activity of serotonin and norepinephrine in spinal pathways, Cymbalta also works to treat various neuropathic and other pain conditions[3] .

Cymbalta requires a prescription from a licensed provider and cannot be obtained over the counter. The medical need for Cymbalta can only be determined by a healthcare professional.

Who Might Benefit From Cymbalta?

Cymbalta is used for the treatment of several conditions, including:

  • Major depressive disorder (MDD) in adults
  • Generalized anxiety disorder (GAD) in patients 7 years of age and older
  • Fibromyalgia in patients 13 years of age and older
  • Diabetic peripheral neuropathic pain and chronic musculoskeletal pain in adults

Cymbalta is also sometimes used off-label for chemotherapy-induced nerve pain and stress urinary incontinence[2] in men and women.

"For many people, Cymbalta works best when combined with talk therapy, such as cognitive-behavioral therapy (CBT), which helps build practical skills for managing thoughts and emotions."
Christina Bookwalter, PharmD
Medical writer and reviewer at MEDvidi

How to Get a Duloxetine (Cymbalta) Prescription Online

A Cymbalta prescription can be obtained in person or online. With MEDvidi, you can get an online prescription for Cymbalta after a detailed assessment. Our medical providers are authorized to prescribe antidepressants through telehealth legitimately and securely. Here is what’s involved in this process:

Step 1: Create an account and book an online appointment

Sign up with your basic personal information, including contact information and medical details. Book a virtual appointment with one of our licensed healthcare providers at a time slot of your choice. Same- or next-day appointments are available.

Step 2: Have an evaluation and treatment

During your appointment, the provider will review your history and symptoms and discuss any treatment options, including Cymbalta. They will go over potential risks, side effects, how long the medication takes to work, alternative options, and anything else you may want to ask. It is important to note that not all consultations will result in a medication prescription. At the end of the appointment, your provider will make the final clinical decision if Cymbalta is medically appropriate for you.

Step 3: Pick up your prescription from a pharmacy

Once your healthcare provider determines that Cymbalta is the most suitable option for you, they will write you a prescription and send it electronically to a pharmacy of your choice. Pick-up or delivery options will vary depending on the pharmacy.

Step 4: Continue with follow-ups and adjustments

It is important to keep regular follow-up appointments with your healthcare provider to make dose adjustments, receive prescription refills, and optimize your treatment plan over time. Be sure to also report any side effects to them to ensure safe, effective use. MEDvidi offers ongoing virtual care for convenience and continuity.

Get assessed for depression and anxiety in 24 hours and receive personalized treatment online.

Cost and Insurance Coverage

The cost of Cymbalta can vary by pharmacy and location, depending on the strength, your insurance plan, and whether you are looking for a brand or generic version. Generic duloxetine can cost $7 to $25 for 30 capsules, while the brand version of Cymbalta can cost upwards of $300.

How to Save

  1. Prices will vary based on which pharmacy you go to. Shop around and compare prices at different pharmacies.
  2. Certain websites like GoodRx and WellRx offer coupons and discount cards that can significantly reduce this price.
  3. Some pharmaceutical companies and non-profit organizations offer assistance to patients who cannot afford their medications, called patient assistance programs. 
  4. Some online pharmacies may offer lower prices than traditional pharmacies.

What to Expect When Taking Cymbalta

When you start taking Cymbalta, there are a few important things to remember. Take this medicine only as directed by your healthcare provider to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your provider ordered.

  • Cymbalta is most commonly taken in capsule form, with or without food. It should not be crushed or chewed.
  • When stopping Cymbalta, the dosage should be gradually decreased to avoid withdrawal symptoms.
  • If you forget to take a dose of your Cymbalta, but remember it before you go to bed, take it straight away. If you do not remember until the next day, skip the missed dose and take your next dose at the usual time. Never take two doses at the same time to make up for a forgotten one.

It is important to share all your symptoms and medical history with your healthcare provider so they can treat you most effectively.

"It takes several weeks to see the full effects of Cymbalta, so it is important to remember to give it time to work. Also, side effects are more common when starting Cymbalta and often improve with time."
Christina Bookwalter, PharmD
Medical writer and reviewer at MEDvidi
Receive ongoing support throughout the whole course of treatment online.

Safety, Side Effects, and Precautions

Common Side Effects

The most common side effects of Cymbalta in adults include nausea, tiredness, constipation, decreased appetite, and sweating. For pediatric patients, the most common effects are weight loss, decreased appetite, nausea, vomiting, fatigue, and diarrhea.

Serious Side Effects

Cymbalta has a boxed warning for increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults. Patients will need to be monitored for any of these mood changes.

Other serious adverse effects of Cymbalta include:

  • Serotonin syndrome
  • Liver changes
  • Mania
  • Fainting
  • Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
  • Hyponatremia (low sodium)

If you’re experiencing suicidal or self-harming thoughts and require immediate assistance, contact a crisis hotline, such as 911, 988 suicide & crisis lifeline (toll-free), or Samaritans (116-123 or via chat).

Drug Interactions and Contraindications

Be aware that Cymbalta may interact with certain antidepressants (fluvoxamine, paroxetine, fluoxetine). It should not be used with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing one. Also, patients who are taking linezolid or have been treated with methylene blue should not use Cymbalta. Please note that this list of interactions is not exhaustive, consult with your provider to learn more.

Some special populations should be considered when taking Cymbalta. These include:

  • Pregnant patients (Cymbalta may cause fetal and neonatal harm).
  • Nursing mothers (Cymbalta is excreted in breast milk and may affect the nursing infant).
  • Elderly (risks of hyponatremia in the geriatric population).

It is vital to disclose all medications and supplements to your provider so they can best protect you from potential interactions.

Alternatives to Cymbalta

Sometimes, alternatives to Cymbalta[3] may need to be considered depending on patient preference. Some other options for the treatment of MDD include:

Why Choose MEDvidi for Mental Health Care?

For concerns related to mental health, MEDvidi provides personalized, nonjudgmental, and ongoing care through an easy-to-follow process. Our licensed and experienced providers offer evidence-based treatment, and same- or next-day appointments. Join MEDvidi today to get help in improving your mental well-being.

Medical providers at MEDvidi are authorized to prescribe Cymbalta after an online consultation in 33 states:

Arizona (AZ), California (CA), Colorado (CO), Florida (FL), Georgia (GA), Idaho (ID), Illinois (IL), Indiana (IN), Kansas (KS), Kentucky (KY), Louisiana (LA), Maine (ME), Maryland (MD), Massachusetts (MA), Michigan (MI), Minnesota (MN), Montana (MT), Nebraska (NE), Nevada (NV), New Mexico (NM), New York (NY), North Carolina (NC), Ohio (OH), Oregon (OR), Pennsylvania (PA), Tennessee (TN), Texas (TX), Vermont (VT), Virginia (VA), Washington (WA), Wisconsin (WI), Wyoming (WY).
MEDvidi is available in these US states

Frequently Asked Questions

Yes, Cymbalta requires a prescription from a licensed provider and cannot be obtained over the counter. The medical need for Cymbalta can only be determined by a healthcare professional.
Licensed healthcare providers such as primary care providers, psychiatrists, nurse practitioners, and physician assistants can prescribe Cymbalta.
A nurse practitioner can prescribe Cymbalta for anxiety and depression treatment, depending on each state’s laws.
Yes, you can purchase Cymbalta out of pocket. Certain websites like GoodRx and WellRx offer coupons and discount cards that can significantly reduce this price.
No, Cymbalta is available only by prescription from a licensed medical provider.

You can buy duloxetine in traditional and legitimate online pharmacies if you have a prescription from your healthcare provider.

Sources

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3 sources
  1. DailyMed - CYMBALTA- duloxetine hydrochloride capsule, delayed release. Nih.gov. Published 2025. Accessed December 18, 2025.
    Source link
  2. Dhaliwal JS, Spurling BC, Molla M. Duloxetine. [Updated 2023 May 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
    Source link
  3. Sheffler ZM, Patel P, Abdijadid S. Antidepressants. [Updated 2023 May 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
    Source link
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Jessica Men
Author:
Jessica Men
PharmD
Christina Bookwalter
Medical Reviewer:
Christina Bookwalter
PharmD
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This article is based on scientific evidence, written by experts and fact checked by experts.

Our team of experts strive to be objective, unbiased, honest and to present both sides of the argument.

This article contains scientific references. The numbers
in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers.