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How to Get Prescribed Antidepressants?

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Our medical team is here to assess your symptoms and provide a prescription for antidepressants if deemed necessary. Book an appointment to get help online.
Written by:
Laura Maleknia
CRNP, FNP-C
Reviewer:
Dr. William Grigg
DO
The medications listed on this website are provided for informational purposes only.
Their inclusion does not guarantee they will be prescribed to any individual, as treatment decisions are ultimately at the discretion of healthcare providers. Healthcare providers may prescribe other medications or recommend non-pharmacological treatment based on the patient’s unique health circumstances and needs. Read more

The majority of antidepressant medications mentioned in this article have a boxed warning, the most serious type of warning from the Food and Drug Administration (FDA). They pose a risk of suicidal thoughts and behaviors. Remember to discuss the risks and keep in touch with your healthcare provider during the whole course of treatment.

Highlights

  • Antidepressants (SSRIs, SNRIs, MAOIs, and others) regulate neurotransmitter levels, helping manage depression and anxiety.
  • Antidepressant medications are available only by prescription.
  • After a thorough assessment, a licensed medical practitioner can prescribe antidepressants online as a part of a treatment plan.

Antidepressants have proven to be effective in treating depression and anxiety but many patients still encounter internalized and social stigma [1*] associated with these conditions and their management. This results in insufficient awareness about adverse reactions and efficacy of antidepressants and may also affect adherence to treatment [2*] .

Open communication and debunking myths are essential for addressing stigma. Read on to learn more about antidepressants, when they can be prescribed, how to obtain a prescription when needed, and what to discuss with a healthcare provider to make an informed decision about available treatments.

Find relief in opening up about depression with a qualified medical provider. Book an online appointment and receive help in 24 hours.

What Are Antidepressants and How Do They Work?

Antidepressants are most commonly used to treat symptoms of depression and anxiety when individuals experience it for a prolonged period of time. 

Our mood is controlled by chemicals in the brain known as neurotransmitters. According to the monoamine hypothesis, an imbalance in neurotransmitters like serotonin, norepinephrine, and dopamine lead to anxiety and depression. Antidepressant medications work by regulating the levels of these neurotransmitters, which helps to relieve symptoms.

Do You Need Antidepressants?

Figuring out whether or not you need antidepressants is a decision made in collaboration with a qualified medical provider. If you are continuously feeling sad, anxious, hopeless, or have suicidal thoughts, and these symptoms start impacting your daily life, it is a sign to plan a mental health consultation. A healthcare professional will thoroughly assess your symptoms along with overall health history and offer suitable solutions.

Antidepressants are more effective in the treatment of severe and chronic depression [3*] rather than mild cases. For mild depression, talk therapy and self-help lifestyle changes are often the first-line choice. Note that the decision is made individually for every patient.

If you’re experiencing suicidal or self-harming thoughts and require immediate assistance, contact a crisis hotline, such as 911, 988 suicide & crisis lifeline (toll-free), or Samaritans (116-123 or via chat).

What Conditions Do Antidepressants Treat?

Antidepressants are primarily formulated to help alleviate major depressive disorder [4*] (MDD) in severe cases when psychotherapy alone is not helpful enough. However, they are also prescribed to manage symptoms of some other mental health conditions, including:

Do You Need a Diagnosis for Antidepressants?

Yes, you need to have a diagnosis provided by a qualified healthcare professional to receive an antidepressant prescription. The process includes an extensive evaluation of your symptoms, their duration and impact on your daily life, medical history, current medications, and other relevant factors such as mood changes and sleep patterns.

After making a diagnosis, a practitioner creates a treatment plan [6*] accordingly. It may or may not include depression medication. If you get prescribed a specific antidepressant, you’ll be provided with detailed instructions on dosage and other aspects of use.

You can begin with taking a standard test for generalized anxiety disorder [7*] or depression. Note that these and similar tools cannot be used for self-diagnosis—they can only show you if there is a need to see a mental health professional. Only a healthcare provider can conduct a comprehensive assessment and make a diagnosis.

"While these medications can significantly improve symptoms of depression and anxiety, it's important for patients to understand that the process involves a thorough evaluation. Each treatment plan must be personalized, and the choice of antidepressant can depend on many factors. Always engage in an open dialogue with your provider to ensure the best treatment approach for your mental health."
Healthcare provider at MEDvidi
Start your journey towards better mental health today. Our medical team is here to help.

How to Get Prescribed Antidepressants

At MEDvidi, you can see a medical provider specializing in depression treatment who can define whether antidepressants are an appropriate treatment option for you. The process includes the following steps:

  1. Sign up: Create an account and provide basic information to book an appointment. 
  2. Book an appointment: Schedule a video call with one of our licensed healthcare professionals at a convenient time slot. 
  3. Initial online consultation: Discuss your symptoms, previous treatments, and medical history in detail with your clinician and ask any questions you have. 
  4. Receive personalized treatment plan: You’ll be provided with a treatment plan according to your individual needs. If your provider thinks antidepressants are needed to manage your symptoms they will issue you a prescription. 
  5. Fill out your prescription: Track the status of your electronic prescription in your Personal Portal and stay informed about the time to collect it at a pharmacy.

Note that some mental health disorders requiring antidepressant medication, such as severe depression, generalized anxiety disorder, and some others, need ongoing monitoring. Discuss the necessity of follow-up appointments with your clinician.

Who Can Prescribe Antidepressants?

Different medical professionals can prescribe antidepressant medications upon assessing patients’ condition

  • Psychiatrists
  • Medical doctors (MDs)
  • Primary care physicians (PCPs)
  • Physician assistants (PAs)
  • Nurse practitioners (NPs)
Healthcare practitioners at MEDvidi are licensed to prescribe antidepressants online if deemed appropriate. Schedule a consultation to learn more.

Getting Depression Medication In-Person

Consulting with a healthcare professional about depression treatment in-person is a similar process to online consultations. During the appointment, discuss your concerns in detail, be it depressive symptoms, the signs of anxiety, or other distressing experiences. After an assessment, you’ll receive personalized recommendations and a treatment plan, including medication prescription if appropriate.

Can Online Doctors Prescribe Antidepressants?

If a healthcare professional is licensed to practice in the same state as the one you reside in they can prescribe medication online, including antidepressants. They can do so only after an appointment involving a thorough evaluation of your symptoms and health history. Medical professionals at MEDvidi are licensed in several states across the US.

Can You Get Antidepressants Over-the-Counter?

No, antidepressant medications aren’t available to purchase over the counter (OTC). They are classified as prescription medications due to potential adverse effects and the need for monitoring. Hence they are subject to strict FDA regulations necessitating a valid prescription from a healthcare practitioner for legal and safe usage.

There are several OTC supplements for managing depressive symptoms, including Omega-3 fatty acids and herbs like St. John’s wort. Note that it’s crucial to consult with a healthcare provider before using them because there is inconclusive evidence [8*] regarding their effectiveness and the risk of serious drug interactions with other medications.

Types of Antidepressants

Following are the various classes of antidepressants [9*] :

  • Selective serotonin reuptake inhibitors (SSRIs): They work by inhibiting the reabsorption of serotonin hence increasing its levels. Examples: citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), and sertraline (Zoloft).
  • Serotonin and norepinephrine reuptake inhibitors (SNRIs): They act by controlling both serotonin as well as norepinephrine reabsorption in the nervous system. Examples: duloxetine (Cymbalta) and venlafaxine (Effexor).
  • Tricyclic antidepressants (TCAs): This type of antidepressant medication works by increasing levels of serotonin and norepinephrine in the brain but they are less selective compared to SSRIs and SNRIs, which increases the risk of side effects. Examples: amitriptyline (Elavil) and imipramine (Tofranil).
  • Monoamine oxidase inhibitors (MAOIs): Monoamine oxidase is an enzyme present in the brain that is involved in removing norepinephrine, serotonin, and dopamine. MAOIs work by inhibiting this enzyme hence increasing neurotransmitter levels. Examples: isocarboxazid (Marplan) and phenelzine (Nardil).
  • Atypical antidepressants: These antidepressants do not fit into any of the above classes. They have multiple mechanisms to help manage depression. Examples: bupropion (Wellbutrin) and mirtazapine (Remeron).

N-methyl-D-aspartate (NMDA): These medications work by inhibiting the use of the NMDA receptor to alleviate symptoms. Only two FDA-approved NMDA antagonist medications are available: esketamine (Spravato) and dextromethorphan/bupropion (Auvelity).

How to Discuss the Use of Antidepressants With a Doctor

If any mental health symptoms disturb you, share your concerns with a healthcare professional to get a diagnosis and appropriate treatment. Here is what is recommended to discuss during an appointment:

  • Describe your symptoms and their effect on your life honestly and in detail.
  • Ask any questions you may have regarding depression medicines or your treatment plan in general.
  • If you are hesitant about taking certain antidepressants, request more information about their effectiveness, side effects and how to deal with them, how long it can take to see the effects, and how to know it’s time to select another treatment. Ask your clinician about modern antidepressants and how they compare to older ones. These questions will help you become more informed about available treatments.
  • Discuss alternative and complementary treatment options for the diagnosed condition.

Questions to Ask Your Clinician About Taking Antidepressants

During your appointment, consider asking the following:

  • Which antidepressant can be most appropriate for my condition and how does it work?
  • What is my prescribed dosage? Can it change over time and what can be a reason for a change?
  • When should I take my medication? Does it make any difference if I take it at a different time?
  • What are the side effects I should look out for, which ones require immediate medical attention?
  • How long will it take for an antidepressant to start working and when does it reach full effects?
  • What should I do if it feels like the medication isn’t working? 
  • What other strategies can I incorporate in my life during treatment to support the effects of antidepressants?
  • When should I have follow-up appointments and why are they necessary? 
  • Which medications or substances should I avoid during antidepressant treatment?
  • Is this medication safe if I am pregnant, breastfeeding or planning to become pregnant? 

In addition, research [10*] shows that patients do not always have sufficient information about side effects of antidepressants, although it’s important to learn about them in advance. Each group of antidepressants and each particular medication may cause a unique set of adverse reaction, but the most common ones include:

  • Gastrointestinal side effects, such as nausea, indigestion, or diarrhea
  • Drowsiness and dizziness
  • Sleep issues or vivid dreams
  • Headaches
  • Decreased libido

A serious potential side effect is serotonin syndrome when the levels of serotonin in the brain become excessively high. This condition might be life-threatening and requires medical attention. Also, the majority of antidepressants have a boxed warning for suicidal thoughts and behaviors. It is important to monitor such symptoms and report them to your clinician as soon as possible. Finally, remember to discuss the course of action in the case you have adverse reactions.

Can You Get Antidepressants Without a Doctor?

Each currently available antidepressant is a prescription medication, so you can’t obtain it without seeing a healthcare professional first. It is necessary to consult with a licensed practitioner online or in person to know if your condition requires antidepressant treatment and receive a prescription.

If it isn’t possible for you to go visit a doctor’s office for any reason, you can use telehealth services such as MEDvidi.

Do not let depression affect your life. Receive an individualized treatment plan at MEDvidi.

How MEDvidi Can Help

MEDvidi offers telemedicine appointments with medical professionals experienced in mental health treatment and licensed to prescribe antidepressant medications online when deemed appropriate. Take the first step toward improving your mental health in a stigma-free environment and receive personalized care from the comfort of your home.

FAQ

You can receive a prescription for antidepressant medication when it is a necessary and appropriate part of your treatment plan for depression, anxiety, or another mental health condition. You have to consult with a medical provider in person or online, go through a symptom assessment, and receive a diagnosis. If deemed appropriate in your case, a clinician will provide you with a prescription.
Yes, your clinician may prescribe antidepressant medications without recommending psychotherapy if it is an appropriate option. However, in most cases, a comprehensive treatment regimen is needed, including medication, therapy, and lifestyle changes.

Common lifestyle recommendations for depression and anxiety that supplement medication management include mindfulness practices, a balanced diet, proper sleep [11*] , regular exercise [12*] , relaxation techniques [13*] , and strong social support. Discuss your individual plan with a medical practitioner.

Some antidepressants may cause excessive sedation or drowsiness when taken along with Suboxone. Because of safety concerns, patients must provide a letter from their clinician indicating that it is appropriate for them to receive an antidepressant while taking Suboxone.

Sources

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13 sources
  1. Shi J, Chen Y, Jiang Y, et al. Stigma and its associations with medication adherence in major depressive disorder. Psychiatry Research. 2024;331:115664.
    Source link
  2. Marasine NR, Sankhi S. Factors Associated with Antidepressant Medication Non-adherence. Turk J Pharm Sci. 2021 Apr 20;18(2):242-249. doi: 10.4274/tjps.galenos.2020.49799. PMID: 33902271; PMCID: PMC8100773.
    Source link
  3. InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Depression: Learn More – How effective are antidepressants? [Updated 2024 Apr 15].
    Source link
  4. Karrouri R, Hammani Z, Benjelloun R, Otheman Y. Major depressive disorder: Validated treatments and future challenges. World J Clin Cases. 2021 Nov 6;9(31):9350-9367. doi: 10.12998/wjcc.v9.i31.9350. PMID: 34877271; PMCID: PMC8610877.
    Source link
  5. Strawn JR, Geracioti L, Rajdev N, Clemenza K, Levine A. Pharmacotherapy for generalized anxiety disorder in adult and pediatric patients: an evidence-based treatment review. Expert Opin Pharmacother. 2018 Jul;19(10):1057-1070. doi: 10.1080/14656566.2018.1491966. PMID: 30056792; PMCID: PMC6340395.
    Source link
  6. Cuijpers P, Noma H, Karyotaki E, Vinkers CH, Cipriani A, Furukawa TA. A network meta-analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression. World Psychiatry. 2020 Feb;19(1):92-107. doi: 10.1002/wps.20701. PMID: 31922679; PMCID: PMC6953550.
    Source link
  7. Spitzer RL. GAD-7 (General Anxiety Disorder-7). MDCalc. Published 2024.
    Source link
  8. Yeung KS, Hernandez M, Mao JJ, Haviland I, Gubili J. Herbal medicine for depression and anxiety: A systematic review with assessment of potential psycho-oncologic relevance. Phytother Res. 2018 May;32(5):865-891. doi: 10.1002/ptr.6033. Epub 2018 Feb 21. PMID: 29464801; PMCID: PMC5938102.
    Source link
  9. Harmer CJ, Duman RS, Cowen PJ. How do antidepressants work? New perspectives for refining future treatment approaches. Lancet Psychiatry. 2017 May;4(5):409-418. doi: 10.1016/S2215-0366(17)30015-9. Epub 2017 Jan 31. PMID: 28153641; PMCID: PMC5410405.
    Source link
  10. Crowe M, Inder DipSoc M, McCall C. The experience of antidepressant use and discontinuation: a qualitative synthesis of the evidence. Journal of Psychiatric and Mental Health Nursing. 2022;30(1).
    Source link
  11. Scott AJ, Webb TL, Martyn-St James M, Rowse G, Weich S. Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials. Sleep Med Rev. 2021 Dec;60:101556. doi: 10.1016/j.smrv.2021.101556. Epub 2021 Sep 23. PMID: 34607184; PMCID: PMC8651630.
    Source link
  12. Xie Y, Wu Z, Sun L, Zhou L, Wang G, Xiao L, Wang H. The Effects and Mechanisms of Exercise on the Treatment of Depression. Front Psychiatry. 2021 Nov 5;12:705559. doi: 10.3389/fpsyt.2021.705559. PMID: 34803752; PMCID: PMC8602192.
    Source link
  13. Toussaint L, Nguyen QA, Roettger C, Dixon K, Offenbächer M, Kohls N, Hirsch J, Sirois F. Effectiveness of Progressive Muscle Relaxation, Deep Breathing, and Guided Imagery in Promoting Psychological and Physiological States of Relaxation. Evid Based Complement Alternat Med. 2021 Jul 2;2021:5924040. doi: 10.1155/2021/5924040. PMID: 34306146; PMCID: PMC8272667.
    Source link
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Written by:
Laura Maleknia
CRNP, FNP-C
Reviewer:
Dr. William Grigg
DO
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This article contains scientific references. The numbers
in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers.