Adderall has a
Highlights
- Dexedrine (dextroamphetamine) and Adderall (amphetamine salts) are both central nervous system (CNS) stimulants.
- Both Adderall and Dexedrine are available in a generic version, which helps to lower their cost.
- Both prescription medications are typically covered by insurance but not always by Medicare.
- Both medications have been shown to reduce ADHD symptom severity.
- Dexedrine can be an alternative to Adderall for those who have seen no improvements while on Adderall or do not tolerate the medication well.
For those with attention deficit hyperactivity disorder (ADHD), stimulant medications are among the most commonly prescribed treatments to help increase focus and tame impulsivity. Dexedrine and Adderall, specifically, are commonly chosen options. However, while they are both CNS stimulants, there are some differences in their formulations.
In this guide, we have compiled the key similarities and differences between these medicines, exploring where Dexedrine equals Adderall and where the strengths of each lie.
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Key Differences Between Dexedrine and Adderall
While both Dexedrine and Adderall are stimulants used to primarily treat ADHD and narcolepsy, their differing active ingredients cause variances in how they affect neurotransmitters in the brain and help manage these conditions.
Dexedrine is a brand-name medication with a generic version of dextroamphetamine sulfate. It stimulates the release of norepinephrine, specifically in the brain’s cerebral cortex. This stimulation then leads to increased motor activity and alertness, decreased fatigue, and an improved mood. Dexedrine is available in immediate-release tablets and Dexedrine Spansules (sustained-release), and its generic version is available in extended-release capsules.
Adderall is a prescription medication that combines amphetamine salts in a 3:1 ratio of dextroamphetamine and levoamphetamine, so it contains the same active ingredient as Dexedrine, dextroamphetamine, as well as other amphetamines. These additional amphetamines allow Adderall to inhibit dopamine reuptake and target the peripheral nervous system—not just the CNS. Adderall is available in both immediate-release tablets and extended-release (Adderall XR), and its dosage comes in a much wider range of strengths compared to the Dexedrine dosage options.
Conditions Treated with Dexedrine and Adderall
Both medications are approved for the treatment of ADHD, which can manifest with a short attention span, impulsivity, and hyperactivity. They are also approved to treat narcolepsy, which is a condition of excessive and uncontrollable daytime sleepiness. If left untreated, it can significantly affect daily functioning.
In addition to these FDA-approved applications, Dexedrine may also be used off-label in the
Adderall also has off-label uses that may include anxiety, depression, and bipolar disorder.
Which Is More Effective: Dexedrine or Adderall?
An
Due to its balanced composition and broader scientific research and approval, Adderall is often a preferred option for ADHD treatment when choosing between the two. However, Dexedrine remains a potential treatment thanks to its ability to reduce symptom severity. For those who do not respond to Adderall, Dexedrine is a common alternative.
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Comparing Dexedrine and Adderall Coverage and Cost
Adderall is often covered by insurance. Coverage by Medicare can vary by plan, although most Medicare Part D and Medicare Advantage plans cover Adderall. If paying out-of-pocket for Adderall, the cost can
Dexedrine is also typically covered by insurance, with variances for Medicare coverage that may require exceptions. The
Both Adderall and Dexedrine are available as generic medications, which can help to reduce out-of-pocket costs. For some insurance and Medicare plans, only the generic versions of these drugs may be covered.
Common Side Effects of Dexedrine and Adderall
Since both medications are prescription stimulants and contain amphetamines as their active ingredients, they have similar potential side effects.
The most common side effects of both
- Dry mouth
- Increased heart rate
- High blood pressure
- Restlessness
- Alopecia
- Trouble sleeping
- Tremor/tics
- Decreased appetite
- Weight loss
- Upset stomach
- Changes in libido
Both medications have also been linked to more serious side effects, including tachycardia and palpitation. In some cases, heart attacks and sudden death have occurred. As such, caution should be exhibited when these stimulants are prescribed to those with pre-existing cardiac abnormalities.
Both stimulant medications are also deemed schedule II narcotic drugs by the
Drug Interaction Risks
Both Dexedrine and Adderall should not be used at the same time as serotonergic drugs, such as tricyclic antidepressants, as they may increase the risk of serotonin syndrome, which can cause the patient to feel dizzy, agitated, have an increased heart rate and even life-threatening consequences.
Additionally, both medications should not be used if someone already takes monoamine oxidase inhibitors (MAOIs), as they slow amphetamine metabolism, which can increase the amphetamine’s effects. As a result, headaches and other signs of hypertensive crisis can occur. If you take blood pressure medication, Dexedrine or Adderall can reduce their effectiveness too, so it’s essential to notify your healthcare provider about all medications you are taking.
Taking herbs or supplements may also affect how Dexedrine or Adderall work in your body and may increase the risk of serious side effects. Always discuss with your doctor not only prescription medications but also any over-the-counter medications and supplements that you currently use.
Important Warnings and Precautions
Adderall and Dexedrine have both been associated with myocardial infarction, strokes, and sudden death in both children and adults—these complications may be more likely to occur in those with pre-existing cardiac conditions.
These ADHD medications can exacerbate behavior disturbances in those who have psychiatric disorders. If CNS stimulants are determined to be the best medication option for these individuals, it is recommended that they be monitored closely. Specifically, those with bipolar disorder may experience mixed or manic episodes while taking either medication.
For those who are pregnant, both medications are pregnancy category C, which means that there are no adequate, controlled studies to establish their safety. As such, these medicines should only be used while pregnant if their benefit clearly outweighs the risk—discuss with your doctor if you become pregnant while taking either medication so that they can help you make this decision.
Before taking Dexedrine or Adderall, it is also important to be aware of allergies. If you have ever experienced an allergic reaction to other stimulants, you should not take Adderall or Dexedrine.
Which One Can Help You?
The mediation that is best for you depends on many factors, including your symptoms, current medications, and health history. In order to find the medication that suits you best, it is crucial that you first find a qualified healthcare provider who will determine which medication is best for your situation based on the benefits and risks in your situation.
Additionally, a key element in determining the greatest fit for a stimulant medication lies in continually updating your doctor about symptom dynamics and side effects. The development of side effects is one of the most common reasons for discontinuing stimulant medication, so informing your healthcare provider, should they develop, can help them mitigate these symptoms or change your prescription entirely.
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How to Get a Prescription for Dexedrine or Adderall
Whether or not you get prescribed Adderall or Dexedrine through MEDvidi depends on your health condition, symptoms, and if your healthcare provider deems it an appropriate treatment. To learn if a stimulant medication is the right option for you and get personalized treatment, follow these steps:
- Step 1: Create an account on MEDvidi, fill in basic information, and schedule an online appointment by choosing a date and time slot that works best for you.
- Step 2: Attend your online ADHD consultation and discuss your symptoms and concerns with a healthcare professional. Following the thorough evaluation, you will receive a treatment plan, which may include medication prescription if it is deemed necessary and determined to be the best choice for your symptoms.
- Step 3: Receive your prescription medication by visiting your local pharmacy. Follow the instructions provided by your doctor for your prescribed dose and report any serious side effects should they develop.
Since both medications are controlled substances, they require a prescription and cannot be purchased over the counter. There may also be stricter guidelines regarding refills, including a limit of 30-day prescriptions and restrictions on how often you can have the medication filled. Your doctor can provide more information regarding the safe usage of Dexedrine or Adderall and what information you need to know.
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Summing Up
Consistent use of the prescribed medication is a key component of successful treatment. Remember to discuss any concerns with your doctor, whether it’s unpleasant side effects or the amount of time needed to see the results. Furthermore, if you would like to switch from Adderall to Dexedrine because of side effects or a difficulty filling an Adderall prescription, discuss the possibility with your healthcare provider.
Both of these medications have the potential to reduce symptoms of ADHD and improve your quality of life, but the key to accomplishing this lies in working with your medical provider to come to the best course of treatment. You can get personalized recommendations on ADHD management at MEDvidi online, book an appointment for a consultation today.
