Stress and anxiety have become a common struggle. However, sometimes, they become severe and may transform into an anxiety disorder, often coming
While psychotherapy and lifestyle changes can help deal with anxiety, some people may need pharmacological support in the beginning. There are various medications available, and among them,
What Is Trazodone?
Trazodone is a prescription medication used for
The way trazodone works in the brain has yet to be fully understood. Currently, it is known to inhibit
Can Trazodone Help With Anxiety?
Different people need different approaches to anxiety treatment. For some, trazodone can be an effective medication, even though it is prescribed for anxiety off-label (meaning the FDA has not approved a medicine for the treatment of that specific disorder). Both on-label and off-label uses may potentially cause side effects, so the choice depends on individual health history.
Effectiveness of Trazodone for Anxiety
In a double-blind, randomized,
In several other studies, trazodone has shown promising results in addressing anxiety-related conditions. In 1987, a
Additionally, a 2001 study suggested that patients taking trazodone coped with insomnia and nightmares linked to post-traumatic stress disorder. These findings collectively indicate the potential effectiveness of trazodone in managing anxiety and related symptoms.
However, trazodone is not among the most commonly prescribed medications and is not the first-line choice for anxiety treatment. Healthcare professionals usually prescribe it when patients are unresponsive to other treatments.
Side Effects and Potential Risks of Trazodone
Like any medication, trazodone has potential side effects and risks. It’s crucial to be aware of these effects to monitor adverse reactions and contact a healthcare provider when necessary.
Common side effects:
- Dizziness
- Drowsiness
- Dry mouth
- Constipation
- Weight gain
Serious side effects:
- Allergic reactions
- Irregular heartbeats
- Mood changes
- Trouble sleeping
- Suicidal thoughts
Trazodone may not be suitable for everyone, so it’s important to discuss your medical history and concerns with your healthcare provider before they prescribe trazodone. They can provide personalized guidance to help you make an informed decision.
Trazodone vs Xanax for Anxiety
Xanax (alprazolam) is one of the commonly prescribed medications for anxiety disorders. It belongs to a class of benzodiazepines and is a short-acting medication that can provide relatively rapid relief from symptoms. This anxiety medicine enhances the effects of a neurotransmitter called GABA, which helps calm the central nervous system.
However, it is essential to note that despite the efficacy of Xanax in treating anxiety, it can be habit-forming and has a high potential for dependence, which is why it is usually prescribed for short-term use. Trazodone is considered to be a safer alternative to Xanax. The choice between them depends on various factors, including the type and severity of anxiety, other existing medical conditions, and the risk of dependence.
Let’s review the main similarities and differences between Xanax and trazodone.
|
Xanax |
Trazodone |
|
|
Drug class |
Benzodiazepine |
Serotonin antagonist and reuptake inhibitor (SARI) |
|
Approved uses |
It is FDA-approved for treating panic disorder and anxiety disorders. It is generally prescribed for short-term use. |
It is FDA-approved as an antidepressant medication used for treating major depressive disorder, but it can be prescribed off-label for anxiety, often in cases where it coexists with sleep disturbances or depression. |
|
Mechanism of action |
It enhances the effects of an inhibitory neurotransmitter GABA, leading to relatively quick relaxation and sedation, compared to some other anti-anxiety medications. |
It modulates the levels of serotonin and other neurotransmitters in the brain, affecting mood and anxiety over time. |
|
Onset of action |
It acts quickly, potentially providing relief within about 30 minutes. However, this period may vary from one patient to another depending on individual factors. |
It may take several weeks of consistent use for the effects on anxiety symptoms to become noticeable. |
|
Duration of action |
It has a short duration of action, typically a few hours. |
It can last longer, especially when used for its sedative effects, and can help improve sleep in addition to relieving anxiety symptoms. |
|
Dependence and drug addiction risk |
It has a high potential for dependence and can be habit-forming. |
It is not considered habit-forming like Xanax. |
Trazodone Dosage
Generally, the dosage of trazodone for anxiety is usually ranging from 150 to 375 mg once daily. However, the dosage may vary depending on the individual health features, the condition being treated, and the doctor’s recommendations. It is essential to follow instructions and not to adjust the dosage on your own. Your healthcare provider will determine the appropriate treatment plan based on your needs and medical history.
Overdosing and the Risk of Addiction
Trazodone is generally considered to have a lower risk of addiction and abuse when compared to some other medications for anxiety. It is not classified as a controlled substance. However, it is crucial to be cautious and use the medication exactly as your doctor prescribes to avoid adverse effects. Taking more than the prescribed dosage can result in an overdose, which can have severe consequences.
If you suspect an overdose or have concerns about trazodone use, seek immediate medical attention or contact a poison control center. Trazodone overdose can affect respiratory, gastrointestinal, cardiovascular, and nervous symptoms, manifesting through symptoms such as:
- Difficulty breathing
- Low blood pressure
- Chest pain
- Nausea
- Vomiting
- Dizziness
- Drowsiness
- Headache
- Lack of coordination
- Seizures
- Sleep issues
Although trazodone overdose is not common, it’s important to remember it may cause life-threatening effects, such as coma or serotonin syndrome.
To reduce the risk of addiction or misuse, take trazodone precisely as directed by your healthcare provider and communicate any concerns or side effects. If you are worried about dependency on trazodone, discuss it with your doctor so they can provide guidance and make necessary adjustments to your treatment plan.
In Conclusion
Trazodone has been found to be a useful medication for managing anxiety. Its effects, combined with its generally lower risk of addiction, make it a compelling treatment option for many people who couldn’t benefit from other treatment options.
Contact our expert medical team if you’re considering medications as part of your anxiety management strategy. We’ll conduct a detailed assessment and provide evidence-based guidance, support, and tailored solutions to help you regain your peace of mind.
